Assistance options and helpful resources

MARGENZA Access Support offers personalized support for patients who have been prescribed MARGENZA and their caregivers.

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Call 1-844-MED-MGNX (1-844-633-6469) to speak with a support specialist who can:

  • Help you or the person you care for enroll in MARGENZA Access Support
  • Answer questions about the Copay Assistance and Patient Assistance Programs
  • Review the eligibility guidelines for the Copay Assistance and Patient Assistance Programs
  • Provide help finding assistance from foundations and charities if you do not have insurance or are not eligible for the Copay Assistance and Patient Assistance Programs

MARGENZA Access Support does not give medical advice and will direct you to your healthcare professional for any questions about your treatment.

The MARGENZA Copay Assistance Program for commercially insured eligible patients

If you have health insurance that is not provided by your state or the federal government—from a job (yours, your spouse’s, or your parent’s) or from a healthcare exchange—then you most likely have what’s called commercial insurance.

The MARGENZA Copay Assistance Program offers eligible patients financial assistance with out-of-pocket costs related to MARGENZA

Here’s how it works: If you are left with a remaining cost after meeting your policy’s copay, the program will pay for the entirety of your remaining cost share, including coinsurance and copays for MARGENZA, up to a maximum of $26,000 during a 12-month period for eligible patients.

Don’t have commercial insurance? We offer a Patient Assistance Program and referrals to Independent Foundations.

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The MARGENZA Patient Assistance Program
Uninsured or underinsured patients who qualify can obtain MARGENZA at no cost.

Patients who meet financial eligibility and other requirements can receive a free year’s supply of MARGENZA.

Independent foundations

Please call MARGENZA Patient Support at 1-844-MED-MGNX (1-844-633-6469) and we can provide a list of independent/third-party foundations that provide funding for cancer patients with financial hardships.

These independent foundations and charities can provide various forms of assistance to patients who qualify under their rules. These foundations are not associated with MacroGenics.

Although we cannot provide information about a foundation’s funding availability, enrollment process, or eligibility guidelines, this information is available from each organization.

Helpful resources

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MARGENZA Patient Brochure

Download for information that can help you or someone you care for understand what to expect from MARGENZA, including treatment benefits, how it works, how it’s given, and more.

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We're here to help

1-844-MED-MGNX (1-844-633-6469)
MARGENZA Access Support is available Monday–Friday 9 AM to 7 PM ET

Important Safety Information

What is the most important information I should know about MARGENZA?
MARGENZA can cause serious side effects, including:
  • Heart problems that may affect your heart’s ability to pump blood. Your doctor will run tests to monitor your heart function before and during treatment with MARGENZA. Based on test results, your doctor may hold or discontinue treatment with MARGENZA.
    • Tell your healthcare provider right away if you get any of the following signs and symptoms: new or worsening shortness of breath, coughing, feeling tired, swelling of the ankles or legs, swelling of the face, irregular heart beat or palpitations, sudden weight gain of more than 5 pounds in 24 hours, dizziness or feeling light-headed, or loss of consciousness.
  • Harm to your unborn baby. Tell your healthcare provider right away if you become pregnant or think you might be pregnant during treatment with MARGENZA. Exposure to MARGENZA during pregnancy or within 4 months prior to conception can result in fetal harm.
    • If you are able to become pregnant, your healthcare provider should do a pregnancy test before you start treatment with MARGENZA.
    • Birth control should be used while receiving MARGENZA and for 4 months after your last dose of MARGENZA.
What are other possible serious side effects of MARGENZA?

Infusion-related reactions. MARGENZA is a medicine that is delivered into a vein through a needle as an infusion. MARGENZA has been associated with infusion-related reactions which can include fever, chills, joint pain, cough, dizziness, tiredness, nausea, vomiting, headache, sweating, fast heart rate, low blood pressure, itching, rash, hives, and shortness of breath. Your healthcare team will monitor you during treatment with MARGENZA and may slow or stop your infusion if you have side effects. You may need to permanently stop MARGENZA if you have a severe infusion reaction.

Before you receive MARGENZA, tell your doctor if you are breastfeeding. It is not known if MARGENZA could pass into breast milk and harm your baby.

What are the most common side effects of MARGENZA in combination with chemotherapy?

The most common side effects with MARGENZA in combination with chemotherapy are fatigue/weakness, nausea, diarrhea, vomiting, constipation, headache, fever, hair loss, abdominal pain, peripheral neuropathy (weakness, numbness, pain, and/or tingling in hands and feet), joint and muscle pain, cough, decreased appetite, shortness of breath, infusion-related reactions, redness/swelling and pain on the palms of the hands and soles of the feet (hand-foot syndrome), and pain in arms and legs.

You are encouraged to report side effects to the FDA at (800) FDA-1088 or or to MacroGenics at (844)-MED-MGNX (844-633-6469).

These are not all the possible side effects of MARGENZA. Your doctor may stop treatment if serious side effects happen. Be sure to contact your healthcare team right away if you have questions or are worried about any side effects.

What does MARGENZA treat?

MARGENZA is a prescription medicine approved for use in combination with chemotherapy for the treatment of adult patients with metastatic HER2-positive breast cancer who have received two or more prior anti-HER2 regimens, at least one of which was for metastatic disease.

Please see full Prescribing Information, including Boxed Warning.