Groups that support the HER2-positive mBC community

We're all in this together

Connect with these organizations that provide vital support to the metastatic breast cancer (mBC) community. Each site offers different types of helpful information.

Click or tap to learn more about each organization.

Tigerlily Foundation logo

Tigerlily Foundation

Tigerlily Foundation’s mission is to educate, advocate for, empower, and support young women–before, during, and after breast cancer; and our vision is to end disparities of age, stage, and color.

Unite for HER logo

Unite For HER

Unite for HER’s mission is to enrich the health and well-being of those diagnosed with breast and ovarian cancer–for life, by funding and delivering integrative therapies.

Metastatic Breast Cancer Alliance logo

MBCA

The Metastatic Breast Cancer Alliance works to unify the efforts of our members to improve the lives of, and outcomes for, those living with metastatic breast cancer and their families through increasing awareness and education about the disease, and progressing research focused on extending life, enhancing quality of life and ultimately... to cure.

Living Beyond Breast Cancer logo

Living Beyond Breast Cancer

Living Beyond Breast Cancer is a national nonprofit organization that fulfills the mission of providing trusted information and a community of support through on-demand, emotional, practical, and evidence-based content that is meaningful to those newly diagnosed, in treatment, post-treatment, and living with metastatic disease.

Young Survival Coalition logo

Young Survival Coalition

YSC is an international organization dedicated to strengthening the community, addressing the unique needs, and improving the quality of life for young adults diagnosed with breast cancer age 40 and under.

Sharsheret logo

Sharsheret

Through personalized support, Sharsheret improves the lives of Jewish women and families living with or at increased genetic risk for breast or ovarian cancer. This national non-profit organization saves lives through educational outreach programs serving all women and men.

Breast Cancer Trials dot org logo

Breast Cancer Trials

BreastCancerTrials.org is a nonprofit, easy-to-use clinical trial matching service that helps people with breast cancer learn about and find trials personalized to their situation. It is a program of Quantum Leap Healthcare Collaborative.

CancerCare logo

CancerCare

CancerCare is the leading national nonprofit organization offering free, professional support services to anyone affected by cancer—including case management, counseling, support groups, educational resources, financial assistance, and more.

These organizations are independent of and not owned or controlled by MacroGenics, which makes no representations about the services and information they may offer. Their inclusion on this website is not intended as an endorsement of the organization or the services offered, nor is it an indication of the organization’s endorsement of MARGENZA.

Personalized support for patients who have been prescribed MARGENZA

LEARN ABOUT MARGENZA ACCESS SUPPORT
Comforting image of doctor holding woman’s hands.

We're here to help

1-844-MED-MGNX (1-844-633-6469)
MARGENZA Access Support is available Monday–Friday 9 AM to 7 PM ET

Important Safety Information

What is the most important information I should know about MARGENZA?
MARGENZA can cause serious side effects, including:
  • Heart problems that may affect your heart’s ability to pump blood. Your doctor will run tests to monitor your heart function before and during treatment with MARGENZA. Based on test results, your doctor may hold or discontinue treatment with MARGENZA.
    • Tell your healthcare provider right away if you get any of the following signs and symptoms: new or worsening shortness of breath, coughing, feeling tired, swelling of the ankles or legs, swelling of the face, irregular heart beat or palpitations, sudden weight gain of more than 5 pounds in 24 hours, dizziness or feeling light-headed, or loss of consciousness.
  • Harm to your unborn baby. Tell your healthcare provider right away if you become pregnant or think you might be pregnant during treatment with MARGENZA. Exposure to MARGENZA during pregnancy or within 4 months prior to conception can result in fetal harm.
    • If you are able to become pregnant, your healthcare provider should do a pregnancy test before you start treatment with MARGENZA.
    • Birth control should be used while receiving MARGENZA and for 4 months after your last dose of MARGENZA.
What are other possible serious side effects of MARGENZA?

Infusion-related reactions. MARGENZA is a medicine that is delivered into a vein through a needle as an infusion. MARGENZA has been associated with infusion-related reactions which can include fever, chills, joint pain, cough, dizziness, tiredness, nausea, vomiting, headache, sweating, fast heart rate, low blood pressure, itching, rash, hives, and shortness of breath. Your healthcare team will monitor you during treatment with MARGENZA and may slow or stop your infusion if you have side effects. You may need to permanently stop MARGENZA if you have a severe infusion reaction.

Before you receive MARGENZA, tell your doctor if you are breastfeeding. It is not known if MARGENZA could pass into breast milk and harm your baby.

What are the most common side effects of MARGENZA in combination with chemotherapy?

The most common side effects with MARGENZA in combination with chemotherapy are fatigue/weakness, nausea, diarrhea, vomiting, constipation, headache, fever, hair loss, abdominal pain, peripheral neuropathy (weakness, numbness, pain, and/or tingling in hands and feet), joint and muscle pain, cough, decreased appetite, shortness of breath, infusion-related reactions, redness/swelling and pain on the palms of the hands and soles of the feet (hand-foot syndrome), and pain in arms and legs.

You are encouraged to report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch or to MacroGenics at (844)-MED-MGNX (844-633-6469).

These are not all the possible side effects of MARGENZA. Your doctor may stop treatment if serious side effects happen. Be sure to contact your healthcare team right away if you have questions or are worried about any side effects.

What does MARGENZA treat?

MARGENZA is a prescription medicine approved for use in combination with chemotherapy for the treatment of adult patients with metastatic HER2-positive breast cancer who have received two or more prior anti-HER2 regimens, at least one of which was for metastatic disease.

Please see full Prescribing Information, including Boxed Warning.